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M J Birrer Selected Research

DMUC5754A

11/2016Phase I study of safety and pharmacokinetics of the anti-MUC16 antibody-drug conjugate DMUC5754A in patients with platinum-resistant ovarian cancer or unresectable pancreatic cancer.

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M J Birrer Research Topics

Disease

10Neoplasms (Cancer)
01/2021 - 08/2000
9Ovarian Neoplasms (Ovarian Cancer)
01/2021 - 05/2004
5Carcinoma (Carcinomatosis)
01/2019 - 06/2000
4Lung Neoplasms (Lung Cancer)
04/2016 - 05/2001
3Neoplasm Metastasis (Metastasis)
01/2021 - 06/2001
2Ovarian Epithelial Carcinoma
01/2021 - 01/2019
2Carcinogenesis
01/2016 - 08/2014
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2008 - 03/2008
2Adenocarcinoma
03/2007 - 08/2000
1Diarrhea
01/2019
1Fatigue
01/2019
1Pancreatic Neoplasms (Pancreatic Cancer)
11/2016
1Chromosome Deletion (Deletion, Chromosome)
08/2014
1Endometrial Neoplasms (Endometrial Cancer)
05/2001
1Ewing Sarcoma (Sarcoma, Ewing)
12/2000
1Primitive Neuroectodermal Tumors (PNET)
12/2000
1Neoplastic Cell Transformation
11/2000
1Adenocarcinoma in Situ
08/2000

Drug/Important Bio-Agent (IBA)

5Proteins (Proteins, Gene)FDA Link
01/2021 - 05/2001
3PlatinumIBA
01/2021 - 11/2016
3Biomarkers (Surrogate Marker)IBA
11/2017 - 12/2013
3DNA (Deoxyribonucleic Acid)IBA
04/2016 - 05/2001
3Transcription Factors (Transcription Factor)IBA
08/2014 - 03/2008
2Paclitaxel (Taxol)FDA LinkGeneric
01/2021 - 04/2013
2liposomal doxorubicin (Doxil)FDA Link
01/2021 - 01/2018
2Immunoconjugates (Immunoconjugate)IBA
01/2018 - 11/2016
2MitogensIBA
12/2008 - 03/2008
2Transcription Factor AP-1 (Transcription Factor AP 1)IBA
12/2008 - 03/2008
2LigandsIBA
05/2004 - 08/2000
2ParaffinIBA
05/2001 - 08/2000
1mirvetuximab soravtansineIBA
01/2021
1Topotecan (Hycamtin)FDA LinkGeneric
01/2021
1Cadherins (E-Cadherin)IBA
01/2021
1Bevacizumab (Avastin)FDA Link
01/2019
1lifastuzumab vedotinIBA
01/2018
1CR 6IBA
11/2016
1AntigensIBA
11/2016
1DMUC5754AIBA
11/2016
1Complement System Proteins (Complement)IBA
01/2016
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
08/2014
1RNA (Ribonucleic Acid)IBA
08/2014
1Pharmaceutical PreparationsIBA
12/2013
1Cisplatin (Platino)FDA LinkGeneric
04/2013
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
12/2008
1Biological ProductsIBA
09/2007
1OligonucleotidesIBA
03/2007
1RetinoidsIBA
05/2004
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2004
1retinamideIBA
05/2004
1FenretinideIBA
05/2004
1Histidine (L-Histidine)FDA Link
06/2001
1Vinblastine (Vinblastine Sulfate)FDA Link
06/2001
1Phosphotransferases (Kinase)IBA
06/2001
1Messenger RNA (mRNA)IBA
05/2001
1Monoclonal AntibodiesIBA
05/2001
1Lovastatin (Mevacor)FDA LinkGeneric
12/2000
1Retinoblastoma ProteinIBA
12/2000
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
12/2000
1Adenosylmethionine DecarboxylaseIBA
11/2000
1Cyclin-Dependent Kinase Inhibitor p27IBA
08/2000
1Transforming Growth Factor beta1 (TGF beta 1)IBA
08/2000
1Transforming Growth Factor beta3 (TGF beta 3)IBA
08/2000
1Formaldehyde (Formol)FDA Link
08/2000
1Transforming Growth Factor beta (TGF-beta)IBA
08/2000
1Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA
08/2000
1Cyclin D1IBA
06/2000

Therapy/Procedure

4Therapeutics
01/2021 - 06/2001
3Drug Therapy (Chemotherapy)
01/2021 - 08/2014
1Precision Medicine
01/2016